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It depends on individual factors, including how much intrinsic factor the body produces

doi: 10.1016/S1470-2045(18)30791-5 68 CascinuSBodokyGMuroKVan CutsemEOhSCFolprechtGet al

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Friedman prefers Tirzepatide over Semaglutide as it gives more weight loss and less side effects but is currently available in CA only in the sublingual form
