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Mechanisms of Disease: metabolic effects of growth hormone and insulin-like growth factor 1
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In addition, RAAS has been shown to decrease the expression of TRPM6 and TRPM7, Mg2+ transporters, which further increases intracellular Mg2+ deficiency [147]
These preclinical models provide the possibility of using a control and treatment groups experimental design, drug interventions, induction of AGIHL and the objective measurement of the hearing function
