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Description
By employing whole-genome haploid screening and CRISPR-Cas9 technology, two pivotal drivers of ferroptosis were identified: Acyl-CoA synthetase long-chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3 (LPCAT3), both of which function as membrane remodeling enzymes [75,76,77]
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Tan M, Li S, Swaroop M et al (1999) Transcriptional activation of the human glutathione peroxidase promoter by p53
doi:10.1016/j.bbagen.2012.09.018
