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Its pathogenesis is complex, involving genetics, dysregulated immune response, environmental factors, and epithelial barrier defects, and it usually occurs in the rectal and colonic mucosa [2]

This dual functionality underscores the complexity of the PD-1 pathway in regulating the balance among exhausted T-cell lineages (Fig

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Yuan H, Zhang Y, Huang S, Yang Y, Gu C (2015) Effects of exogenous glutathione and cysteine on growth, lead accumulation, and tolerance of Iris lactea var