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The concentration of all metabolites was calculated relative to the unsuppressed water spectrum and expressed as %water signal (IMCL and EMCL) or in absolute concentration values (all other metabolites) calculated using the following formula: Where [M] is the metabolite concentration and [W] is the water concentration (55 M)

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An analysis of the transcriptomic profile of RILI in non-human primates revealed that the expression of SERPINA3, ATP12A, GJB2, CLDN10, TOX3, and LPA was significantly up-regulated, suggesting their potential as biomarkers and therapeutic targets for RILI [103]