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doi: 10.1038/s41588-018-0058-3

Wattanakrai, P., & Nimmannitya, K

3.1.3 Primary defects of the synthesis or activity of IGF-1 and IGF-2 This category of defects includes defects of the synthesis of IGF-1 and IGF-2 due to gene mutation, abnormalities of the IGF-1 receptor, bio inactive IGF-1, and defects of IGFBP-3 or ALS

The published data for aflibercept in the first quarter of 2019, for example, shows an HCPCS code dosage of 1 mg and a payment limit of $963.537 per unit billed
