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In in vivo experiments, the Siv-PMB@G4@MM group showed minimal lung injury and a reduced inflammatory response ( Figure 3G )
In recent years, IDH inhibitors targeting IDH mutants, including ivosidenib and enasidenib (Table 1), have been approved by the Food and Drug Administration to be used in patients with IDH1 or IDH2 mutant recurrent or refractory AML, respectively (Kim, 2017
