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GOT1 knockout combined with cysteine depletion by erastin or IKE showed potent antitumor effects against these cells by reducing GSH and increasing ferroptosis 66
Studies have also revealed that NLRP3 protein localizes to mitochondria in GCs and accumulates around the nucleus, where the inflammatory cascade exacerbates mitochondrial damage and induces ROS production [73]
ICD-10-CM Chapter 15 (Pregnancy, Childbirth, and the Puerperium) and Chapter 16 (Perinatal Conditions) take precedence
Brain 143 , 512530 (2020)
