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We show that a decrease in thalamic GABA levels over time is related to new onset migraine in previously unaffected adolescents (t(41.4)=2.79, p=0.008) and increased disease burden in those who previously experienced migraine (b=-0.01, SE=0.003, p<0.001)

In addition, depending on the level of failure, many metabolic disorders, especially anemia, occur
