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Furthermore, some newer agents for metastatic hormone-sensitive PCa may require more extensive preclinical testing in multiple models and need to demonstrate better synergistic effects with standard-of-care agents before introduction into clinical trials
The protocol rewards patience GH-mediated recomp is slow and cumulative, not rapid like stimulants
NADP(H) 4 , linking the two redox systems
First, as a GSH-dependent peroxide reductase, GPX4 activity highly depends on cystine provided by System Xc /SLC7A11 to maintain GSH synthesis
