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This crosstalk amplifies neuroinflammatory signaling and alters neurovascular integrity, contributing to blood-brain barrier disruption, glial priming, and neuronal injury 11-12
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In another study by Savransky et al[93] in mice and in obese humans, C57BL/6J mice were exposed to CIH or normoxia for 10 wk while being treated with SCD-1 or control antisense oligonucleotides
found that leukocytes may induce sperm DNA damage with cascade amplification effects, while affected patients have significantly increased ROS production rates and reduced sperm motility
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