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With respect to ferroptosis, the use of mitochondria-targeted ROS scavenger mitoquinone (MitoQ), which also increases GSH levels, could preserve mitochondria integrity and protect cells from lipid peroxide accumulation and subsequent cell death

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Figure 5 Discussion Studies involving colorectal cancer have revealed that T2DM-related traits, such as hyperglycaemia and hypoinsulinaemia, increase the risk of disease and cancer-specific mortality while lowering disease-free and overall survival in CRC patients ( Based on TCGA database analysis, We discovered that the expressions of IGF-1, IGF1R and RAGE in colorectal cancer tissues were different from those in normal tissues

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