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Targeting DC antigen presentation or their interaction with CD8 + T cells could therefore disrupt a key step in the autoimmune cascade
Peptides are complex molecules composed of amino acid chains that face unique challenges when administered to biological systems

& Stern, M

A wide spectrum of pathogenetic mechanisms underly DPN with oxidative stress, inflammation with the release of proinflammatory cytokines and mitochondrial dysfunction being the major contributors [10]
