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sapiens FLVCR2 with choline bound FLVCR proteins belong to the major facilitator superfamily (MFS), topologically consisting of 12 transmembrane helices that are arranged in an N domain (M1M6) and a C domain (M7M12) around a central twofold symmetry point (Fig 3A) (18, 35)

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In this case, females tend to favor males who exhibit territoriality and have strong mating calls (the basis for this is selfish as it lies in the female's desire for the greatest reproductive success and the best traits to be passed down to their offspring)