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An overdose of Bedoyecta can cause impaired liver and kidney function
As a result, methylfolate is converted to tetrahydrofolate, which is required for purine synthesis which in turn is required for DNA synthesis
[2,8] Metformin may reduce serum B12 levels by causing B12 to accumulate in the liver.[8] For example, randomized controlled trials of patients taking metformin for an average of 4.3 years had a ~20% decrease in B12 levels and a 7% increased risk of B12 deficiency compared to placebo
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