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First, CMS only allowed MGCRB reclassifications for 412.103 hospitals when the hospital's wages are at least 106 percent of the urban area in which it was geographically located, rather than the rural area to which it was reclassified under 412.103 ( see 81 FR 56925)

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It also suppresses the invasion and metastasis of cancer cells by downregulating the expression of various matrix metalloproteinases (MMPs), including MMP-2 (Lee et al., 2015), MMP-9 (Yodkeeree et al., 2009

Impairment of short-chain fatty acid (SCFA) and l-isoleucine biosynthesis in gut microbiome persists beyond 30 days after recovery from COVID-19, which could contribute to persistent leaky gut and dysbiosis in PASC patients 237,238