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There are more nerves in the muscle in the thigh than in the deltoid muscle, and it is easier to find the safe place to do the injection in the upper arm (which is why this is a common used place to give vaccinations i.m.)

When your body receives the B12 shot, it begins to absorb more of the nutrient than usual, which can cause a spike in energy levels

The reaction consumes the universal cellular methyl donor SAM and the NAD + salvage precursor nicotinamide, producing a metabolite (1-MNA) that is excreted in urine

Folic acid is absorbed in the small intestine and reduced to tetrahydrofolate (THF) with the help of the enzyme dihydrofolate reductase