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Brain and Development 32:105109 Williams TA, Mars AE, Buyske SG, Stenroos ES, Wang R, Factura-Santiago MF, Lambert GH, Johnson WG (2007) Risk of autistic disorder in affected offspring of mothers with a glutathione S-transferase P1 haplotype

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It is currently being tested in a phase 2 clinical trial, placebo controlled, to study its efficacy and safety in patients with SCD during VOC (ClinicalTrials.gov Identifier: NCT02515838) (Telen et al., 2016)

440 To address this issue, researchers have integrated different peptides or functional domains capable of overcoming transfer barriers into a single peptide-based carrier to enhance delivery efficiency