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We also detected a significant drop in total GSH in ADH5 cells, which might indicate that the active efflux of HSMGSH could contribute to a drop in the net cellular GSH thus also affecting cellular redox homeostasis (Fig

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This reaction is catalyzed by the enzyme serine hydroxymethyltransferase, a vitamin B6-containing enzyme

In 2002, Arai and co-workers reported studies involving epoxidation reactions of menadione ( 10 ) using H 2 O 2 as oxidant and a chiral salt derived from cinchonine PTC 44 as catalyst