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Participants with normal hepatic function were eligible for inclusion if they were judged to be of general good health by the investigator, based on a medical examination (including physical examination, medical history, vital signs and ECG) and had liver enzyme levels within prespecified limits (alanine aminotransferase upper limit of normal [ULN] + 10%, aspartate aminotransferase ULN + 20% and total bilirubin ULN + 20%)

NEWTON, J.F., YOSHIMOTO, J., BERNSTEIN, J., RUSH, G.F., & HOOK, J.B

Strengthens the skin's protective barrier and supports joint function

Whether long-term treatment with mecobalamin in T2DM patients with DPN harms sleep should be assessed in a future longitudinal study