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In addition, many mechanistic insights remain far from clinically actionable treatment options, and very few intervention approaches have been evaluated in rigorous large-scale prospective trials

& Ryznar, R

28 However, naltrexone should be avoided in those with acute liver failure or decompensated cirrhosis

DCMF 16S rRNA gene copy numbers were converted to cell numbers by dividing by four (the number of 16S rRNA genes in the genome)
