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[DOI] [PMC free article] [PubMed] [Google Scholar] 173.Scott J.M
39 The Pivotal Function of IRAK4 in Triggering the IL-1R/TLR Pathway within HS When a ligand binds to IL-1R/TLR, IRAK4 is attracted to the MyD88 oligomerization complex
Therefore, targeting the TRIM22/NRF2 axis may represent a promising therapeutic strategy for the treatment of oxidative stress [108]
Additionally, GLO-1 expression demonstrated strong associations with both inhibitory and stimulatory ICPs, such as CD276, VEGFA, and HMGB1, across a majority of the analyzed cancer tissues
