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Dabei hat sie die Eigenschaft, die Blut-Hirn-Schranke zu passieren, was therapeutisch vor allem bei Schwermetallbelastungen im Gehirn und dem zentralen Nervensystem von groem Vorteil ist

In the open trial, which aimed to test the clinical efficacy of creatine supplementation in a large cohort of patients, myopathies included muscle dystrophies ( n = 15), mitochondrial cytopathies ( n = 17), inflammatory myopathies ( n = 14), and peripheral neuropathy disorders ( n = 18), whereas the single-blinded study was conducted only on 21 heterogeneous patients ( n = 16, miscellaneous myopathies, n = 6 muscle dystrophies, n = 1 peripheral neuropathy disorder, and n = 1 inflammatory myopathy [53]

Nutrient interactions Large doses of pantothenic acid have the potential to compete with biotin for intestinal and cellular uptake by the human sodium-dependent multivitamin transporter (hSMVT) (39, 50)

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