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Nicotinamide mononucleotide protects against - amyloid oligomer-induced cognitive impairment and neuronal death

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Using the combinations of stable isotope ( 13 C) tracers, NMR and GCMS profiling, and isotopomer spectral analysis (ISA), we found that APAP-treated HepG2 cells exhibit an enhanced Warburg effect, in that lactate production from glucose exceeded the already elevated levels of cancer cells, leading to rapid depletion of glucose from the media
