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Clinical studies and meta-analyses suggest that ALA supplementation can lead to small but meaningful improvements in fasting glucose and insulin sensitivity, particularly in people with type 2 diabetes or metabolic syndrome.2 24 That said, these effects are generally modest and ALA should never be viewed as a substitute for prescribed diabetes medications

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These effects are generally no more bothersome than what you might feel after a flu shot or a routine blood draw

For warfarin: increase INR checks from monthly to biweekly for the first month, then weekly if any bruising or bleeding signs appear