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The ongoing degradation of NRF2 ensures that only the basal expression levels of NRF2 target genes are maintained, supporting essential housekeeping functions

Studies in cell culture lines suggest its role in reducing cell death and improving the functions of the thymus and fetal heart

However, different patterns in the up- or downregulation of biomarkers were observed due to different concentrations tested by both laboratories (i.e., tested concentrations range from 0.0050.2 g/cm 2 or 0.19.4 g/cm 2 in Laboratories 1 and 2, respectively)

4 Future perspectives SFN has become a promising phytochemical in the treatment of several diseases in the last few years, including various cancers, autism spectrum disorder, schizophrenia, obesity, and fatty liver disease