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The ex vivo synthesized sequences of FAPCAR were cloned into IVT template plasmid as the ORF region which also carried T7 promoter, modified 5 UTR, kozak sequence, 3 UTR, and a 110 nt-long poly (A) tail 59,60,61
There is no direct human cancer signal in current data -- but there is also no dataset proving neutrality across long-duration use
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