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Pyrogallol, another downstream metabolite, was found to enhance HO-1 expression in human umbilical cord mesenchymal stem cells (hUCMSCs), potentially strengthening their antioxidant and anti-inflammatory capabilities in an LPS-induced acute lung injury (ALI) model (Zhang et al., 2022), although direct suppression of inflammatory mediators was not explicitly demonstrated

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Blood cancers can disrupt bone marrow function and reduce healthy red blood cell production

[ 15 ] Linker chemistry is another determinant: stable amide linkers can reduce Tcell activation, whereas thioesters may enhance recognition, depending on their persistence during antigen processing
