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Waseem et al., 2022)

In agreement with previous studies on other oxaliplatin-based platinum(IV) prodrug systems 44 , the overall cellular accumulation of BSO-OxOAc was distinctly lower than of oxaliplatin in both cell models (Fig

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We also identified classes of mutations that are highly informative in sequencefunction studies: activating mutations, separation-of-function mutations and mutations that selectively tune the activity of the oncogenic BDC