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Social Signal Transduction Theory of Depression
E.McClainT.CarterS.PerlmutterD
However, Heinz bodies are a very transient finding because they tend to be promptly pinched off by the spleen (thus giving rise to bite cells), and the red blood cells that contain them are very rapidly removed from the circulation
Furthermore, peroxidation of lipids present in the brain creates a toxic product called acrolein, which is a potent inhibitor of lipoate-containing proteins, such as PDH [180, 204, 205]
