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Domitrovich, A

10.1093/cercor/10.10.927 [DOI] [PubMed] [Google Scholar] Thanseem I., Nakamura K., Miyachi T., Toyota T., Yamada S., Tsujii M., et al

These pain-relieving effects are blocked by drugs that affect norepinephrine, but not serotonin, suggesting that the pain relief works through adrenergic pathways (9)