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Description
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It would therefore be conceivable that development of ligands capable of specifically activating signalling complexes with the least capacity to trigger the regulatory mechanisms underlying tolerance could result in more prolonged analgesic actions than those of currently available opioids
The starting dose is 0.25 mg weekly for four weeks, increasing to 0.5 mg once a week
The following information is drawn exclusively from published animal research and is presented for educational purposes relating to research methodology only
