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Description

Once mycotoxins enter the body through inhalation, ingestion, or skin contact, they trigger a cascade of effects: Immune dysregulation , mycotoxins can suppress or overstimulate immune pathways, creating chronic inflammation without effective pathogen clearance Mitochondrial damage , mycotoxins impair electron transport chain function, reducing cellular energy production Oxidative stress , mycotoxin metabolism generates reactive oxygen species that damage cell membranes, DNA, and proteins Hormonal disruption , certain mycotoxins are endocrine disruptors that affect cortisol, thyroid, and sex hormone pathways Neuroinflammation , mycotoxins cross the blood-brain barrier and trigger glial cell activation, producing brain fog, memory issues, and mood changes Approximately 25% of the population carries HLA gene variants that impair their ability to recognize and clear biotoxins efficiently

Acknowledgements The authors are thankful to the Deanship of Scientific Research, King Khalid University, Abha, Saudi Arabia, for financially supporting this work through the Large Research Group Project under Grant no