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Curcumin administration has been associated with beneficial changes in gut microbiota composition, leading to improved intestinal barrier function and reduced endotoxin levels that may contribute to liver inflammation through toll-like receptor (TLR) pathways

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Kikidis D, Vassou E, Markatos N, Schlee W, Iliadou E

While it remains a source of controversy, cholinomimetics (primarily bethanechol ) are to increase smooth muscle tone and reduce urinary retention sometimes used 2)