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The findings of two different studies on the relationship between sleep disturbances and AA present conflicting results

Other studies have reported that DSF treatment alone can effectively enhance in vivo anti-cancer immunity, which are attributed to mechanisms independent of Cu, such as inducing PD-L1 up-regulation by suppressing DNMT1 expression and activity [61] or inhibiting the accumulation and polarization of tumor-suppressive macrophages by targeting FROUNT [23]

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Wu C, Thalhamer T, Franca RF, Xiao S, Wang C, Hotta C, Zhu C, Hirashima M, Anderson AC, Kuchroo VK
