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Activation of plaque macrophages by other immune cells through CD40TRAF6 signaling triggers NF-B activation, amplifies pro-inflammatory cytokine secretion, promotes macrophage polarization towards the M1 phenotype, and enhances immune cell recruitment, collectively contributing to the progression of atherosclerosis
C.Khanal LamichhaneA.ChungK
Strikingly, the change reversed at the end of the two months of the high-stress period
doi: 10.1186/s12943-022-01500-4 2 WangYBaiCRuanYLiuMChuQQiuLet al
