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(3) 72 hours later, the rats are anesthetized and immediately perfused transcardially with 50 mL 0.9% saline followed by 500 mL 0.1 m neutral phosphate-buffered formaldehyde (4%)
Subsequent high-resolution LC-MS/MS quantification further validated the significantly diminished fecal IPA levels in CD patients versus healthy controls (Fig
Meanwhile, A and hyperphosphorylated tau can directly inhibit the nuclear translocation and transcriptional activity of Nrf2, impairing the axiss function in regulating antioxidant and iron metabolic balance
