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The applicant further stated that the Breakthrough Device designation applies to two clinical scenarios: a de novo system where a patient receives the Aveir TM Dual-Chamber Leadless Pacemaker, or an upgrade system where a patient already has a ventricular leadless pacemaker and is upgraded to the Aveir TM Dual-Chamber Leadless Pacemaker by receiving the Aveir TM AR Leadless Pacemaker

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Pharm Nanotechnol 10:2441 Ahn H, Park J-H (2016) Liposomal delivery systems for intestinal lymphatic drug transport

doi: 10.2139/ssrn.4487594 81
