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A.Van den BoschL.PintelonI.Mohey-ElsaeedO.BolsP

FR Expression and Function in the Adult Brain In the adult brain, FR remains abundant in the choroid plexus

Isoiza Ojo, Department of Chemistry, University of Kentucky, Lexington, Kentucky 40506, United States

During the 7-day treatment schedule, MP-13 maintained stable antinociception without tolerance development, as evidenced by the unchanged microglial cell count in the periaqueductal gray, indicating that chronic exposure did not trigger neuroinflammatory adaptationa process in which microglia become activated, release pro-inflammatory cytokines, and contribute to opioid tolerance
