elevated creatine kinase and aldolase melanotan Proximal weakness elevation in systemic sclerosis: Clinical correlates, prognosis and functional implications Proposed mode of action of
Description
Thanassoulis G, Campbell CY, Owens DS, Smith JG, Smith AV, Peloso GM, Kerr KF, Pechlivanis S, Budoff MJ, Harris TB, Malhotra R, O'Brien KD, Kamstrup PR, Nordestgaard BG, Tybjaerg-Hansen A, Allison MA, Aspelund T, Criqui MH, Heckbert SR, Hwang SJ, Liu Y, Sjogren M, van der Pals J, Kalsch H, Muhleisen TW, Nothen MM, Cupples LA, Caslake M, Di AE, Danesh J, Rotter JI, Sigurdsson S, Wong Q, Erbel R, Kathiresan S, Melander O, Gudnason V, O'Donnell CJ, Post WS

Acetylcarnitine can also improve mitochondrial biosynthesis, quality control and dynamics by increasing the levels of peroxisome proliferator-activated receptor coactivator 1 (PGC-1) and mitochondrial DNA (mtDNA) [16]

Rabar S, Harker M, O'Flynn N, Wierzbicki AS, Grp GD

Oct 2023;26(10):2066-2075
