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Amplite Rapid Fluorimetric Glutathione GSH/GSSG Ratio assay uses a water-soluble sensor Thiolite Green 520WS

described that ultrafiltrate platinum AUC after ePIPAC was similar to that of after IV oxaliplatin at 90 mg/m 2 , and higher than that of PIPAC (Lurvink et al., 2021)

The mechanisms through which a low insulin drive with enhanced FoxO activation may contribute to longevity include a metabolic shift from glucose to lipid oxidation, with concomitant enhancement of cellular stress resistance and protection, suppression of inflammation and enhanced mitochondrial biogenesis (Figure 2)