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Metabolic Studies: This compound is valuable in studying lipid metabolism and energy production in cells, making it essential for researchers exploring metabolic disorders
Moreover, in head and neck squamous cell carcinoma, CAFs increase the stromal stiffness of the tumor niche by remodeling the biomechanical properties of the TME
[DOI] [PMC free article] [PubMed] [Google Scholar] 691
The increase in sphingomyelins can interfere with signaling pathways, including phosphatidylinositol 3-kinase (PI3K)/AKT and MAPK, inhibiting cancer cell proliferation and growth (222)
