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Despite 50 years of sales and more than 30,000 published papers, there remain unknowns about acetaminophen

World J Gastroenterol 2008;14:313-7

Manolikakes G

Signals of thiomethyl metabolites were always low for blood samples collected less than 6h apart, showing that elimination of NAPQI (either after conjugation to glutathione or the antidote) is also subject to a delay in case of acute intoxication
