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Similar content being viewed by others Background The gastrointestinal (GI) mucosal epithelium is one of the largest tissue systems that maintain constant interaction with the external environment

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In the SURMOUNT-1 trial published in the New England Journal of Medicine , once-weekly Tirzepatide produced dose-dependent reductions in body weight over 72 weeks in adults with obesity or overweight, with the highest-dose arm showing some of the strongest weight-loss outcomes reported at the time for an incretin-based therapy