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Description
TB-500 may inhibit apoptosis in corneal epithelial cells by inhibiting caspases and suppressing the release of pro-apoptotic protein bcl-2 from mitochondria

These hypotheses, however, failed to describe PSC patients without IBD and those who develop PSC prior to the development of IBD

10.1016/j.ijcard.2012.12.048 100

Additionally, research is exploring the optimal use of these medications in various patient populations
