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If you want the rationale behind dosing frequency (and why people commonly discuss daily vs weekly approaches), see BPC-157 TB-500 Half-Life: Why Daily Dosing Beats Weekly
however, it does so at the expense of applying the same weight, which is inconsistent with previous decisions about apply differential weighting to measures to incentivize HHAs to act on improving measures with higher weights in the applicable measure set as outlined in the CY 2022 HH PPS final rule (86 FR 62322)
These studies cannot include deficient subjects, thus also limiting their clinical relevance
