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After transient MCAO, CD163 macrophages upregulated the expression of the hypoxia-inducible factor-1 (HIF-1) pathway, vascular endothelial growth factor (VEGF), inducible nitric oxide synthase (iNOS), and chemoattractants, leading to neurological impairment [125, 126]

Epidermal growth factor receptor inhibitors in development for the treatment of non-small cell lung cancer

10.1016/0895-4356(93)90053-4 65 WHO (2021)

If you have any existing concerns regarding your kidney function, it is important to speak with a healthcare provider before starting any new supplement
