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GEVALnull was used as an unresponsive negative control

Although we cannot rule out that the increased production of ROS in 3D culture conditions may not be observed under hypoxia, it should be noted that hypoxia itself induces ROS production in numerous cell types, including tumor cells [39]

doi: 10.3168/jds.2009-2693 102 PeagaricanoF.SouzaA

The 5th biomedical engineerings recent progress in biomaterials, drugs development, and medical devices: proceedings of the 5th International Symposium of Biomedical Engineering (ISBE) 2020
