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Zheng J, Jiang R, Chen M et al (2018) Multi-copper ferroxidase-deficient mice have increased brain iron concentrations and learning and memory deficits

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ROS can be classified in two groups: - Free radicals (superoxide, the hydroxyl radicals, lipid peroxy-radicals, and alkoxy radicals)

Enzymatic Endogenous Antioxidants These have a high relevance for ageing, inflammation, and post procedure recovery Superoxide dismutase (SOD) Catalase Glutathione peroxidase CLINICAL RELEVANCE: These decline with age, are reduced by UV exposure and pollution and as they are important for post inflammatory and wound healing processes , its important to note that older patients receiving skin treatments may have delayed healing and post recovery because of their decline