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5mCG is mainly located at intergenic regions, repetitive DNA regions, and silenced genes, directly interfering with the binding of certain transcriptional regulators to their cognate DNA sequences or recruiting repressive methyl-CpG binding domain (MBD) proteins [33, 35]
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Recent findings indicate that 7nAChR activation may cause pathological angiogenesis in diabetic retinopathy by boosting VEGF expression [310, 311]
Natural antioxidants (Vitamin E and Selenium)support muscle cell integrity and reduce free radical damage
